ANGIO-SEALĀ® (VIP Vascular Closure Device)
PRODUCT OVERVIEW

BIOABSORBABLE COMPONENTS
The device creates a mechanical seal by sandwiching the arteriotomy between a bioabsorbable anchor and collagen sponge, which dissolve in 60 to 90 days.
Three bioabsorbable components actively seal the arteriotomy:
- Anchor: Bioabsorbable co-polymer anchor placed against the inside of the vessel wall
- Collagen: Placed on top of the arteriotomy in the tissue tract
- Suture: Cinches the anchor and collagen together to form a secure seal.
LOCATE THE ARTERY
- Exchange the procedure sheath with the Angio-Seal locator system.
- Blood flow through the locator visually confirms proper sheath position in the artery.
SET THE ANCHOR
- Insert the Angio-Seal VIP device into the sheath until you hear a āclick.ā
- Gently pull back on the locking cap until you hear another āclick.ā
- The anchor is now locked in place and device is ready to be deployed.
SEAL THE PUNCTURE
- Gently pull back on the Angio-Seal VIP device until the suture has stopped spooling.
- Maintain upward tension on the device and gently advance the compaction tube until resistance is felt.
- Cut the suture and remove the device.
ANGIO-SEAL VIP PRODUCT CODES
| Part Number | French Size | Guidewire Diameter (in) |
| 610130 | 6Fr | .035 Wire |
| 610131 | 8Fr | .038 Wire |
REFERENCES
RX ONLY. Refer to the product labels and package insert for complete warnings, precautions, potential complications, and instructions for use.Ā
- Nash JE, Evans DG. (1999). The AngioāSeal hemostatic puncture closure device. Concept and experimental results. Herz, 24(8), 597ā606.
- Per Instructions For Use ASIN0004 revision 2018-09-01.
Indications:
TheĀ Angio-Seal Vascular Closure Device product family, including the VIP and Evolution platforms, is indicated for use in closing and reducing time to hemostasis of the femoral arterial puncture site in patients who have undergone diagnostic angiography procedures or interventional procedures using an 8 French or smaller procedural sheath for the 8 F Angio-Seal device and a 6 French or smaller procedural sheath for the 6 F Angio-Seal device.Ā The Angio-Seal VIP and Evolution platform devices are also indicated for use to allow patients who have undergone diagnostic angiography to safely ambulate as soon as possible after sheath removal and device placement, as well as to allow patients who have undergone an interventional procedure to safely ambulate after sheath removal and device placement.
Important Safety Information:
Possible adverse events for vascular closure devices include, but are not limited to: bleeding or hematoma, AV fistula or pseudoaneurysm, infection, allergic reaction, foreign body reaction, inflammation or edema. This device should only be used by a licensed physician (or other health care professional authorized by or under the direction of such physician) possessing adequate instruction in the use of the device, e.g., participation in an Angio-Seal physician instruction program or equivalent.
ANGIO-SEALĀ® (VIP Vascular Closure Device)
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OCTOPUS TISSUE STABILIZER
OctopusĀ
TissueĀ Stabilizers
OCTOPUS TISSUEĀ STABILIZERS
Our newest generation tissue stabilizer features automatic pod spread for effective visualization.
SUMMARY
OCTOPUS EVOLUTION AS ā THE NEXT GENERATION TISSUEĀ STABILIZER
The newest generation tissue stabiliser from Medtronic demonstrates an enduring commitment to the cardiac surgeon. With all the same features of the Octopus⢠Evolution ā enhanced stability, flexibility, and a lower profile for unlimited positioning options ā the Octopus Evolution AS offers an automatic pod spread feature that enhances visibility at the anastomotic site.
- Automatic pod spread for effective visualisation of the anastomotic site
- Very secure arm for maximumĀ stabilization
- Greater flexibility enables unlimited positioning options
- Simple, secure, one-handed attachment of clamp to the retractor
OCTOPUS EVOLUTION ā LOW PROFILE WITH FLEXIBILITY AND REACH
The Octopus Evolution stabilizerĀ provides enhanced stability, flexibility, and a lower profile for unlimited positioning options.
Enhanced stability and flexibility features:
- Improved visualisation with:
- Lower profile headlink
- Surgeon controlled pod-spread
- Allowance for multiple device positions including pods-up, pods-down and pods-to-the-side applications
- Increased flexibility and range of motion
- Longer, effective reach of the articulating arm provides easier access to all vessels
- Simple, secure, one-handed engagement of clamp and turret assembly
THE OCTOPUS 4.3 STABILISER FEATURES SUPERIOR ARM STRENGTH AND UNMATCHED STABILITY IN THE CLAMP/TURRET MECHANISM.
- Dual vacuum tubes offer superior tissue capture
- Internal cable enables arm twisting for maximum access and flexibility
- Reinforced arm links offer better stabilisation
- Whale tail tightens easily
- Swivel turret offers access while maximising visualisation
- Head lock design allows ātoes upā position, pod spread and bend
- Rigid clamp designed to eliminate rocking
OCTOPUS 4 ā EXCELLENT STABILITY AND FLEXIBILITY
The Octopus 4 tissue stabiliser includes innovative features, such as clear, malleable pods combined with a smaller diameter, more flexible arm, and an ultra-low headlink profile.
- Pod spreading optimises sewing space and stability of anastomotic site
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Coronary Diagnostic Catheter (OPTITORQUE)
PRODUCT OVERVIEW
A complete line of coronary diagnostic catheters designed for superior torque control and precise placement.
RADIAL-SPECIFIC UNIVERSAL SHAPES
- Radial Specific curves designed to enable support and alignment during catheterization1
- Excellent back-up support for angiography of both RCA and LCA with a single catheter1,a
- Universal design eliminates the need for catheter exchanges and potentially shortens procedural and fluoroscopic time
1. DOF Reference
a. when compared to leading competitors
2. Ikaria article.ĀOPTITORQUE Classic Shapes
Shape Category Product Code
5 Fr / 1.70 mmProduct Code
6 Fr / 2.00 mmShape Name (cm) Length Holes Side Tip Shape Pigtail 40-5030 40-6030 Straight Pigtail 110 6 40-5031 40-6031 Angled Pigtail 155° 110 6 Judkins Left 40-5040 40-6040 JL 3.5 (Judkins Left 3.5 cm) 100 40-5041 40-6041 JL 4.0 (Judkins Left 4.0 cm) 100 40-5042 40-6042 JL 5.0 (Judkins Left 5.0 cm) 100 Judkins Right 40-5043 40-6043 JR 3.5 (Judkins Right 3.5 cm) 100 40-5044 40-6044 JR 4.0 (Judkins Right 4.0 cm) 100 40-5045 JR 5.0 (Judkins Right 5.0 cm) 100 Bypass 40-5050 40-6050 Internal Mammary 100 Amplatz 40-5060 AL 1 (Amplatz Left Small Type) 100 40-5061 40-6061 AL 2 (Amplatz Left Middle Type) 100 UNIQUE DESIGN
- Designed for coaxial alignment to the ostium, allowing the catheter to sit at the appropriate angle for optimal engagement
- Large lumen allows high flow of contrast media and allows downsizing of French size
PROVEN PERFORMANCE
- Superior torqueability for precise placement1,a
- Excellent trackability in tortuous anatomy while navigating the radial artery1,a
- Superior flow rates for diagnostic imaging1,a
1.DOF
a. When compared to leading competitorsĀ -
RESOLUTE INTEGRITY STENT
Resolute Onyx DES
for coronary artery disease
Resolute Onyx⢠is a drug-eluting stent (DES) that’s different by design, optimised for complex PCI, and proven safe and effective in real-world, high bleeding risk patients on 1-month dual antiplatelet therapy (DAPT).1
Resolute Onyx DES is different by design to address your DES needs and a wide range of patient anatomies.Ā It features:
- Best-in-classĀ deliver ability
- Enhanced visibility with thinner struts
- Smooth side branch access
- Fast healing
- The broadest diameter range
Best-in-class deliverability
Single-wire design
Resolute Onyx DES is made from a single wire, which gives it a fluid range of motion and provides the flexibility needed for best-in-class deliverability.2

Sinusoid-formed wire

Helical wrap

Laser-fused
Competitive comparison
Resolute Onyx DES is more deliverable than laser-cut SYNERGYā¢* XD and XIENCE Skypointā¢*, which are stiffer.
Ā
Deliverability comparison ā 3.0 mm DES2
(Lower is better)

Enhanced visibility with thinner struts
Platinum-iridium core within Resolute Onyx DES increases visibility for accurate stent placement without compromising strut thickness.2Average visibility comparison2
(Higher is better)

- Cobalt alloy shell
- Platinum iridium core

Resolute Onyx cobalt alloy shell and platinum-iridum core
Smooth side branch access
Resolute Onyx DES has round struts to create a smooth passage when accessing the side branch and lower the propensity to catch during bifurcation procedures.2
Strut comparison
Rounded strut cross-section
- Resolute Onyx DES

Square strut cross-section
- SYNERGYā¢* DES
- XIENCEā¢*Ā DES

Broadest diameter range
- Complex PCI requires a broad DES size matrix to match a wide range of patient anatomies.
- Resolute Onyx is the only DES with diameters ranging from 2.0 mm to 5.0 mm to treat a broad range of coronary vessel sizes.
Diameter (mm) Ā Ā Ā Ā Ā Ā Ā Ā Ā Stent Length (mm) Maximum Expansion
Capabilities (MSIDā ) (mm)Ā2.00 8 12 15 18 22 26 30 ā ā 3.50ā” 2.25 8 12 15 18 22 26 30 34 38 3.50ā” 2.50 8 12 15 18 22 26 30 34 38 3.50ā” 2.75 8 12 15 18 22 26 30 34 38 4.00ā” 3.00 8 12 15 18 22 26 30 34 38 4.00ā” 3.50 8 12 15 18 22 26 30 34 38 5.00ā” 4.00 8 12 15 18 22 26 30 34 38 5.00ā” 4.50 ā 12 15 18 22 26 30 ā ā 6.00ā” 5.00 ā 12 15 18 22 26 30 ā ā 6.00ā” PRODUCT DETAILS
2.00 RONYX20008X RONYX20012X RONYX20015X RONYX20018X RONYX20022X RONYX20026X RONYX20030X N/A N/A 2.25 RONYX22508X RONYX22512X RONYX22515X RONYX22518X RONYX22522X RONYX22526X RONYX22530X RONYX22534X RONYX22538X 2.50 RONYX25008X RONYX25012X RONYX25015X RONYX25018X RONYX25022X RONYX25026X RONYX25030X RONYX25034X RONYX25038X 2.75 RONYX27508X RONYX27512X RONYX27515X RONYX27518X RONYX27522X RONYX27526X RONYX27530X RONYX27534X RONYX27538X 3.00 RONYX30008X RONYX30012X RONYX30015X RONYX30018X RONYX30022X RONYX30026X RONYX30030X RONYX30034X RONYX30038X 3.50 RONYX35008X RONYX35012X RONYX35015X RONYX35015X RONYX35022X RONYX35026X RONYX35030X RONYX35034X RONYX35038X 4.00 RONYX40008X RONYX40012X RONYX40015X RONYX40018X RONYX40022X RONYX40026X RONYX40030X RONYX40034X RONYX40038X 4.50 N/A RONYX45012X RONYX45015X RONYX45018X RONYX45022X RONYX45026X RONYX45030X N/A N/A 5.00Ā N/A RONYX50012X RONYX50015X RONYX50018X RONYX50022X RONYX50026X RONYX5
















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